Green Tea Catechins and Ibuprofen
Supplement–drug interaction evidence from the TruthStack database.
| Severity | LOW |
|---|---|
| Evidence Tier | Limited |
| Interaction Type | NEUTRAL |
| Last Reviewed | 2026-02-24 |
Summary
No significant interaction documented.
CYP Enzyme Profiles
Published CYP enzyme data for compounds in this interaction:
Green Tea Catechins: CYP1A2 substrate (moderate), CYP3A4 inhibitor (weak)
Ibuprofen: CYP2C9 substrate (strong)
Shared Pharmacodynamic Endpoints
Both compounds influence the same physiological endpoints in the same direction:
| Endpoint | Direction | Green Tea Catechins | Ibuprofen |
|---|---|---|---|
| PLATELET FUNCTION | DECREASE | WEAK | MODERATE |
Cumulative effect on shared endpoints may exceed individual compound profiles. This is relevant to discussion with a prescribing clinician.
What We Don't Know
This interaction has limited evidence. Key gaps may include: direct clinical trial data for this specific combination, dose-response relationships, and long-term outcome data. Absence of evidence is not evidence of absence.
API Reference
Open, unauthenticated. Returns JSON. Developer documentation