Ginkgo Biloba and Omega-3
Supplement–drug interaction evidence from the TruthStack database.
| Severity | MODERATE |
|---|---|
| Evidence Tier | Moderate |
| Interaction Type | SAFETY CONCERN |
| Mechanism | PHARMACODYNAMIC |
| Last Reviewed | 2026-02-15 |
Summary
Additive anti-platelet/anticoagulant effects; bleeding risk. Monitor for bruising; stop both 2 weeks pre-surgery
Higher-Concern Contexts
This interaction may be of particular concern in the following contexts:
- anticoagulant use
CYP Enzyme Profiles
Published CYP enzyme data for compounds in this interaction:
Ginkgo Biloba: CYP1A2 inducer (weak), CYP2C9 inhibitor (weak), CYP3A4 inducer (weak)
Shared Pharmacodynamic Endpoints
Both compounds influence the same physiological endpoints in the same direction:
| Endpoint | Direction | Ginkgo Biloba | Omega-3 |
|---|---|---|---|
| COAGULATION | DECREASE | MODERATE | WEAK |
| PLATELET FUNCTION | DECREASE | MODERATE | MODERATE |
Cumulative effect on shared endpoints may exceed individual compound profiles. This is relevant to discussion with a prescribing clinician.
API Reference
GET https://api.truthstack.co/v1/check?c1=Ginkgo%20Biloba&c2=Omega-3
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.