Curcumin and Resveratrol

Supplement–drug interaction evidence from the TruthStack database.

SeverityMODERATE
Evidence TierModerate
Interaction TypeSAFETY CONCERN
MechanismPHARMACODYNAMIC
Last Reviewed2026-02-15

Summary

Both are mTOR inhibitors; taking within 4h of resistance training blunts muscle protein synthesis. Consider taking 4+ hours away from resistance training

CYP Enzyme Profiles

Published CYP enzyme data for compounds in this interaction:

Curcumin: CYP1A2 inhibitor (weak), CYP2C9 inhibitor (moderate), CYP2D6 inhibitor (weak), CYP3A4 inhibitor (moderate)

API Reference

GET https://api.truthstack.co/v1/check?c1=Curcumin&c2=Resveratrol

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

Apixaban + Curcumin Clopidogrel + Curcumin Curcumin + Rivaroxaban Resveratrol + Tacrolimus Amlodipine + Turmeric Atorvastatin + Turmeric Citalopram + Turmeric Duloxetine + Turmeric
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.