Aspirin and Curcumin
Supplement–drug interaction evidence from the TruthStack database.
| Severity | LOW |
|---|---|
| Evidence Tier | Limited |
| Interaction Type | BLEEDING RISK |
| Mechanism | PHARMACODYNAMIC |
| Last Reviewed | 2026-02-15 |
Summary
Curcumin and aspirin both have antiplatelet properties. Combined bleeding risk at typical supplement doses. Monitor. Discuss with your prescriber or pharmacist.
CYP Enzyme Profiles
Published CYP enzyme data for compounds in this interaction:
Curcumin: CYP1A2 inhibitor (weak), CYP2C9 inhibitor (moderate), CYP2D6 inhibitor (weak), CYP3A4 inhibitor (moderate)
What We Don't Know
This interaction has limited evidence. Key gaps may include: direct clinical trial data for this specific combination, dose-response relationships, and long-term outcome data. Absence of evidence is not evidence of absence.
API Reference
GET https://api.truthstack.co/v1/check?c1=aspirin&c2=curcumin
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.